General Information

  • ID:  hor003509
  • Uniprot ID:  P85832
  • Protein name:  Orcokinin
  • Gene name:  NA
  • Organism:  Apis mellifera (Honeybee)
  • Family:  Orcokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  LTNYLATTGHGTNTGGPVLT
  • Length:  20
  • Propeptide:  MPRHSVFALSILALSITATVWIPTVQAETNLLRREFYGPVNPELFAAFLDDHDARGRENQRDFSSGSGTNELVDELSPVSERETLERFGKRNIDEIDRTAFDNFFKRNLDEIDRVGWSGFVKRLTNYLATTGHGTNTGGPVLTRRFG
  • Signal peptide:  MPRHSVFALSILALSITATVWIPTVQA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-P85832-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003509_AF2.pdbhor003509_ESM.pdb

Physical Information

Mass: 232727 Formula: C86H138N24O30
Absent amino acids: CDEFIKMQRSW Common amino acids: T
pI: 7.54 Basic residues: 1
Polar residues: 13 Hydrophobic residues: 5
Hydrophobicity: -7.5 Boman Index: -913
Half-Life: 5.5 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 78
Instability Index: -1189.5 Extinction Coefficient cystines: 1490
Absorbance 280nm: 78.42

Literature

  • PubMed ID:  17068263
  • Title:  From the Genome to the Proteome: Uncovering Peptides in the Apis Brain